Build a Mapping table rather than using nested SUBSTITUTE. A comparison key can be =LOWER(TRIM(SUBSTITUTE(A2,"-"," "))), but the mapping table remains authoritative.
Apply with =IF(A2="","Missing",XLOOKUP(LOWER(TRIM(SUBSTITUTE(A2,"-"," "))),Mapping[NormalizedKey],Mapping[CanonicalLabel],"Review")). Do not add closed until its 12 rows are resolved from other evidence. Summarize counts by raw and canonical value; the mapped total plus Review must equal 160. Store mapping version and approval date so future imports can be reproduced.